Robustness at every step
True robustness comes from the entire workflow — not from any single step. Every component of the Neogen® Molecular Detection System™ (MDS) is designed to perform reliably and work seamlessly together as an integrated system.
From optimized sample processing and advanced DNA isolation to robust LAMP amplification and reliable bioluminescent detection, every step contributes to the performance of the whole. The result is a simplified, high-performance platform purpose-built for food safety laboratories.
Innovation at every step
What it does:
- Optimized enrichment conditions optimized for target recovery
Why it matters:
- Helps ensure that the target organisms are detectable before testing begins
What it does:
- Advanced lysis solution with nanotechnology-based DNA cleanup
- Colorimetric temperature process control
Why it matters:
- Binds and neutralizes inhibitors — even from complex food matrices
- Colored processing indicates that the lysis step was successfully completed
What it does:
- LAMP-based isothermal amplification using Bst DNA polymerase
Why it matters:
- Continuous, single-temperature amplification rapidly generates target DNA copies for sensitive detection.
- Robust amplification helps minimize the impact of inhibitors commonly found in food matrices, supporting reliable detection.
What it does:
- Bioluminescent reporting system signals DNA amplification.
Why it matters:
- Eliminates the need for fluorescence optics, enabling a simpler, more robust instrument design with easier maintenance.
- Less susceptible to signal quenching from sample matrices, supporting reliable signal detection.
Pathogen detection is as easy as 1,2,3
01
ENRICH
An optimized enrichment protocol that will allow the growth and recovery of a target pathogen.
02
DETECT
Specific Molecular Detection Assays which provide all elements for sample preparation and DNA detection.
03
ANALYZE
A Molecular Detection instrument for target DNA amplification and real-time signal detection, with integrated software for result interpretation.
Speed That Drives Business Decisions
Speed isn't just a lab metric — it's a business advantage that touches your bottom line. The Neogen Molecular Detection System delivers next-day results, with presumptive positives identified in as little as 15 minutes.
In practice, this early-read capability changes how quickly you can act. This early indication allows the lab to begin confirmation testing sooner and deliver results to clients faster, supporting faster decisions and more timely action regarding product disposition.
For food producers, time-to-decision has a direct impact on profit and losses. The sooner results are available, the sooner products can be released or held — reducing the risk of spoilage, shortening product hold times, and minimizing waste from goods waiting on test results.
Combined with a streamlined, single-protocol workflow, the Molecular Detection System helps your team make confident release decisions faster — protecting product quality, reducing waste, and keeping your supply chain moving.
Bst DNA Polymerase: The Engine Behind LAMP
LAMP continuously amplifies DNA at a single temperature using strand- displacing Bst DNA polymerase and multiple pairs of primers. This unique amplification mechanism rapidly generates large amounts of target DNA while maintaining robust performance across complex sample matrices. LAMP has demonstrated high sensitivity and specificity, along with a proven tolerance to common inhibitory substances found in food and environmental samples.¹
¹ Ref: Becherer L, et al. Loop-mediated isothermal amplification (LAMP) – review and classification of methods for sequence-specific detection. Analytical Methods. 2020;12:717–746. /small>
Hardware and Software, Designed to Work Together
MDS100: A Compact Instrument
- Portable, space-saving design that fits any lab
- Flexibility to test up to 96 samples in each run
- Quick, cost-saving calibration—just send your unit to our facility for expert service
- Global service with local support teams
User-Friendly Software
- User-friendly software with intuitive user interface for quick and easy setup
- Real-time results help make critical decisions faster
- Color-coded assays by organism and matching software screens allow for better tracking and easy identification
- Flexible, multi-pathogen testing in a single run
Why QuanTEM Food Safety Laboratories Switched to LAMP
Check out our blog, "Using Neogen® Molecular Detection System: Q&A with QuanTEM Food Safety Laboratories," to learn more about the technology.