BetaStar® Advanced for Beta-lactams

Item No.  BSA002

  • Test for all six regulated beta-lactam antibiotics in just five minutes
  • Analyze with Neogen’s Raptor® reader, which can test three samples at once
This item has shipping restrictions.
$430.68 each
In stock
Out of stock
Expect availability in 2-4 weeks
Minimum quantity required: 1
This item must be ordered in multiples of one case. Quantity per case: 1

Just add milk

BetaStar® Advanced for Beta-lactams is a rapid detection test for penicillin, ampicillin, amoxicillin, cloxacillin, cephapirin and ceftiofur in raw, commingled cow milk, offering results in just five minutes. It holds approvals from the AOAC-RI and the National Conference on Interstate Milk Shipments. BetaStar Advanced is designed to work exclusively with Neogen’s state-of-the-art Raptor Integrated Analysis Platform, which controls the volume, temperature and runtime of up to three test strips at once — allowing you to simply add milk and walk away.

Brand BetaStar®
Analyte Beta-lactams
Platform Lateral Flow
Result Type Qualitative
Time to Result 5
Incubation Time 5
Quantity per Package 100 tests
Package Dimensions 8.10 in x 5.20 in x 9.40 in
Package Weight 1.00 lb

The BetaStar Advanced for Beta-lactams kit contains:

  1. 100 test strips for detecting beta-lactams
  2. 100 test cartridges
  3. 100 disposable 400 μL poly-pipettes
  1. Raptor Integrated Analysis System (Neogen item number: 9680)
  2. Dymo Label Writer 450 Printer (Neogen item number: 9687)
  3. Dymo replacement paper (Neogen item number: 9688)
  4. Raptor Verification Standards (cartridges containing test strip standards) (Neogen item number: 9685)
  5. BetaStar Advanced Positive Control (Penicillin G at 5.0 ± 0.5 ppb; Desfuroylceftiofur at 100 ± 10 ppb) (Neogen item number: BSA010)

Additional Information

BetaStar Advanced Performance Information

ppb Amoxicillin Ampicillin Ceftiofur Cephapirin Cloxacillin Penicillin
0 0% 0% 0% 0% 0% 0%
1 0%
2 0% 0% 0%
3 0%
4 0% 0% 0% 90%
5 100%
6 27% 0%
7 27% 97%
8 73% 100% 50%
10 100% 100% 100%
14 33%
16 73%
18 100%
20 100%
50 0%
60 13%
80 80%
90 97%
100 100%
Tolerance/safe level (ppb) 1 10 10 100 20 10 5
Calculated 90 – 95% 2 9.24 ppb 8.57 ppb 92.66 ppb 18.07 ppb 9.03 ppb 4.63 ppb

1 The tolerance level for each of the tetracycline antibiotics has been set by the FDA as the sum of all tetracyclines.

2 The 90/95 sensitivity level was calculated from data collected during validation testing by a third party laboratory. Sensitivity was based on testing multiple levels of each beta-lactam antibiotic samples per concentration.


The milk is wicked through a reagent zone, which contains antibodies and receptors conjugated to colloidal gold particles. If beta-lactams or ceftiofur are present, they will be captured by their particle-antibody complex. The drug-antibody-particle complex then is wicked onto a membrane. The membrane contains two separate and independent test lines, with one consisting of a drug conjugated to a protein carrier designed to capture the beta-lactams and the other test line consisting of a drug-protein conjugate designed to capture ceftiofur. These independent test lines capture any antibody / receptor gold particle complexes (in absence of antibiotics) to concentrate and form a visible line. As the level of a particular drug in the sample increases, free drug molecules will complex with the antibody/receptor gold particles. This allows less antibody-gold to be captured into the test lines. Therefore, as the concentration of a drug in the sample increases, the test line density decreases. The membrane also contains a control line where an immune complex present in the reagent zone is captured by an antibody, forming a visible line. The control line will always form regardless of the presence of the drug, ensuring the strip is functioning properly.



Our customers’ success is our shared success. Our experts are ready to train you and your team on our solutions, so you can rest easy knowing procedures are performed properly and yield accurate results. In addition, we provide certificates upon completion of training to provide you with the documentation needed for audit traceability.



Our experts are here to help. If you need information beyond what is provided in Validation Reports under the Documents tab, please contact us and we will be happy to assist you. Learn more