BetaStar® Advanced for Beta-lactams
Item No. BSA002
- Test for all six regulated beta-lactam antibiotics in just five minutes
- Analyze with NEOGEN’s Raptor® reader, which can test three samples at once
Just add milk
BetaStar® Advanced for Beta-lactams is a rapid detection test for penicillin, ampicillin, amoxicillin, cloxacillin, cephapirin and ceftiofur in raw, commingled cow milk, offering results in just five minutes. It holds approvals from the AOAC-RI and the National Conference on Interstate Milk Shipments. BetaStar Advanced is designed to work exclusively with NEOGEN’s state-of-the-art Raptor Integrated Analysis Platform, which controls the volume, temperature and runtime of up to three test strips at once — allowing you to simply add milk and walk away.
| Specifications | |
|---|---|
| Analyte | Beta-lactams |
| Approvals | AOAC-RI; FDA; NCIMS |
| Brand | BetaStar® |
| Incubation Time | 5 |
| Package Dimensions | 8.10 IN x 5.20 IN x 9.40 IN |
| Package Weight | 1.00 LB |
| Platform | Lateral Flow |
| Quantity per Package | 100 tests |
| Result Type | Qualitative |
| Time to Result | 5 Minutes |
Additional Information
BetaStar Advanced Performance Information
| ppb | Amoxicillin | Ampicillin | Ceftiofur | Cephapirin | Cloxacillin | Penicillin |
| 0 | 0% | 0% | 0% | 0% | 0% | 0% |
| 1 | 0% | |||||
| 2 | 0% | 0% | 0% | |||
| 3 | 0% | |||||
| 4 | 0% | 0% | 0% | 90% | ||
| 5 | 100% | |||||
| 6 | 27% | 0% | ||||
| 7 | 27% | 97% | ||||
| 8 | 73% | 100% | 50% | |||
| 10 | 100% | 100% | 100% | |||
| 14 | 33% | |||||
| 16 | 73% | |||||
| 18 | 100% | |||||
| 20 | 100% | |||||
| 50 | 0% | |||||
| 60 | 13% | |||||
| 80 | 80% | |||||
| 90 | 97% | |||||
| 100 | 100% | |||||
| Tolerance/safe level (ppb) 1 | 10 | 10 | 100 | 20 | 10 | 5 |
| Calculated 90 – 95% 2 | 9.24 ppb | 8.57 ppb | 92.66 ppb | 18.07 ppb | 9.03 ppb | 4.63 ppb |
1 The tolerance level for each of the tetracycline antibiotics has been set by the FDA as the sum of all tetracyclines.
2 The 90/95 sensitivity level was calculated from data collected during validation testing by a third party laboratory. Sensitivity was based on testing multiple levels of each beta-lactam antibiotic samples per concentration.
Documents
Technology
The milk is wicked through a reagent zone, which contains antibodies and receptors conjugated to colloidal gold particles. If beta-lactams or ceftiofur are present, they will be captured by their particle-antibody complex. The drug-antibody-particle complex then is wicked onto a membrane. The membrane contains two separate and independent test lines, with one consisting of a drug conjugated to a protein carrier designed to capture the beta-lactams and the other test line consisting of a drug-protein conjugate designed to capture ceftiofur. These independent test lines capture any antibody / receptor gold particle complexes (in absence of antibiotics) to concentrate and form a visible line. As the level of a particular drug in the sample increases, free drug molecules will complex with the antibody/receptor gold particles. This allows less antibody-gold to be captured into the test lines. Therefore, as the concentration of a drug in the sample increases, the test line density decreases. The membrane also contains a control line where an immune complex present in the reagent zone is captured by an antibody, forming a visible line. The control line will always form regardless of the presence of the drug, ensuring the strip is functioning properly.
Training
Our customers’ success is our shared success. Our experts are ready to train you and your team on our solutions, so you can rest easy knowing procedures are performed properly and yield accurate results. In addition, we provide certificates upon completion of training to provide you with the documentation needed for audit traceability.